4UZ9
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VII - SOS COMPLEX - 2.2A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN NOTUM HOMOLOG | polymer | 383 | 43567.1 | 1 | UniProt (Q6P988) Pfam (PF03283) | HOMO SAPIENS (HUMAN) | |
| 2 | B (B) | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose | branched | 982.8 | 1 | In PDB BIRD (PRD_900013) | sucrose octasulfate | ||
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 81 - 451 (UniProt: Q6P988)
| PDB | External Database | Details |
|---|---|---|
| Glu 78 | - | expression tag |
| Thr 79 | - | expression tag |
| Gly 80 | - | expression tag |
| Gly 452 | - | expression tag |
| Thr 453 | - | expression tag |
| Lys 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
| Ser 330 | Cys 330 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43567.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 982.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 256.7 | |
| All* | Total formula weight | 44806.6 |






