4UZ9

STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VII - SOS COMPLEX - 2.2A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PROTEIN NOTUM HOMOLOG	polymer	383	43567.1	1	UniProt (Q6P988) Pfam (PF03283) In PDB	HOMO SAPIENS (HUMAN)
2	B	1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose	branched		982.8	1	In PDB BIRD (PRD_900013)		sucrose octasulfate
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5		water	water		18.0	115	Chemie (HOH)

Sequence modifications

A: 81 - 451 (UniProt: Q6P988)

PDB	External Database	Details
Glu 78	-	expression tag
Thr 79	-	expression tag
Gly 80	-	expression tag
Gly 452	-	expression tag
Thr 453	-	expression tag
Lys 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
Ser 330	Cys 330	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43567.1
Branched	Number of molecules	1
	Total formula weight	982.8
Non-Polymers*	Number of molecules	2
	Total formula weight	256.7
All*	Total formula weight	44806.6

*Water molecules are not included.