4UYI

Crystal structure of the BTB domain of human SLX4 (BTBD12)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4	polymer	152	16740.7	1	UniProt (Q8IY92) Pfam (PF00651)	HOMO SAPIENS (HUMAN)	BTB/POZ DOMAIN-CONTAINING PROTEIN 12, SLX4
2	B (A)	water	water		18.0	93	Chemie (HOH)

Sequence modifications

A: 668 - 796 (UniProt: Q8IY92)

PDB	External Database	Details
Met 645	-	expression tag
His 646	-	expression tag
His 647	-	expression tag
His 648	-	expression tag
His 649	-	expression tag
His 650	-	expression tag
His 651	-	expression tag
Ser 652	-	expression tag
Ser 653	-	expression tag
Gly 654	-	expression tag
Val 655	-	expression tag
Asp 656	-	expression tag
Leu 657	-	expression tag
Gly 658	-	expression tag
Thr 659	-	expression tag
Glu 660	-	expression tag
Asn 661	-	expression tag
Leu 662	-	expression tag
Tyr 663	-	expression tag
Phe 664	-	expression tag
Gln 665	-	expression tag
Ser 666	-	expression tag
Met 667	-	expression tag
Ile 729	Val 729	engineered mutation
Glu 734	Leu 734	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16740.7
All*	Total formula weight	16740.7

*Water molecules are not included.