4UXU
Crystal Structure of the Extracellular Domain of the Human Alpha9 Nicotinic Acetylcholine Receptor In Complex with Methyllycaconitine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 | polymer | 218 | 25307.0 | 2 | UniProt (Q9UGM1) Pfam (PF02931) | HOMO SAPIENS (HUMAN) | NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9, NACHR ALP HA-9, HUMAN ALPHA9 NICOTINIC ACETYLCHOLINE RECEPTOR |
| 2 | C, K (A, B) | METHYLLYCACONITINE | non-polymer | 682.8 | 2 | Chemie (MLK) | |||
| 3 | D, E, L, N (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 4 | F, G, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | H, O (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | I, J, P, Q (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 7 | R, S (A, B) | water | water | 18.0 | 502 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 212 (UniProt: Q9UGM1)
| PDB | External Database | Details |
|---|---|---|
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50614.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3435.8 | |
| All* | Total formula weight | 54049.9 |
