4UXU
Crystal Structure of the Extracellular Domain of the Human Alpha9 Nicotinic Acetylcholine Receptor In Complex with Methyllycaconitine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 | polymer | 218 | 25307.0 | 2 | UniProt (Q9UGM1) Pfam (PF02931) | HOMO SAPIENS (HUMAN) | NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9, NACHR ALP HA-9, HUMAN ALPHA9 NICOTINIC ACETYLCHOLINE RECEPTOR |
| 2 | C, K (A, B) | METHYLLYCACONITINE | non-polymer | 682.8 | 2 | Chemie (MLK) PubChem (16401493) PubChem (22209998) PubChem (23307250) PubChem (24207107) PubChem (24848438) PubChem (25075992) PubChem (25200048) PubChem (16759265) PubChem (21550736) PubChem (22525004) PubChem (23350326) PubChem (25077276) PubChem (25200052) PubChem (42617558) PubChem (42617557) PubChem (44567311) PubChem (44575473) PubChem (42617556) PubChem (49874180) PubChem (176519955) PubChem (177560881) PubChem (107640) PubChem (441748) PubChem (72201037) PubChem (90479750) PubChem (90661977) PubChem (5288811) PubChem (5311278) PubChem (102601949) PubChem (118718698) PubChem (122173074) PubChem (124604697) PubChem (9874729) PubChem (126479971) PubChem (9939771) PubChem (127025916) PubChem (129010075) PubChem (129447850) PubChem (129490900) PubChem (10919507) PubChem (131664598) PubChem (54604862) PubChem (134865857) PubChem (11969093) PubChem (11972613) PubChem (137326926) PubChem (139292146) PubChem (157630782) PubChem (163024200) PubChem (165147107) PubChem (165339349) PubChem (166177171) PubChem (168011766) PubChem (171318713) PubChem (171378657) PubChem (172430940) PubChem (172873984) PubChem (172938275) PubChem (90661716) PubChem (90661963) PubChem (90661966) PubChem (122361535) PubChem (494471) PubChem (5459119) PubChem (6426938) PubChem (6604691) PubChem (9961534) PubChem (129447851) PubChem (129447852) PubChem (129447853) PubChem (11969792) PubChem (132427697) PubChem (134865859) PubChem (134865861) PubChem (134865862) PubChem (134866294) PubChem (134866465) PubChem (138404422) PubChem (139215932) PubChem (163024196) PubChem (163024197) PubChem (163024198) PubChem (163024199) PubChem (163024201) PubChem (163024202) PubChem (163337811) PubChem (168008662) PubChem (168012028) PubChem (168315407) PubChem (170999944) PubChem (171039738) PubChem (171318715) PubChem (171350122) PubChem (172021418) PubChem (172038947) PubChem (172049488) PubChem (172432072) PubChem (173803415) | |||
| 3 | D, E, L, N (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) PubChem (23831) | |||
| 4 | F, G, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | H, O (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 6 | I, J, P, Q (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 7 | R, S (A, B) | water | water | 18.0 | 502 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 212 (UniProt: Q9UGM1)
| PDB | External Database | Details |
|---|---|---|
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50614.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3435.8 | |
| All* | Total formula weight | 54049.9 |
