4UX9

Crystal structure of JNK1 bound to a MKK7 docking motif

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	MITOGEN-ACTIVATED PROTEIN KINASE 8	polymer	364	42096.7	4	UniProt (P45983) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	MAP KINASE 8, MAPK 8, JNK-46, STRESS-ACTIVATED PROTEIN KINASE 1C, SAPK1C, STRESS-ACTIVATED PROTEIN KINASE JNK1, C-JUN N-TERMI NAL KINASE 1, JNK1
2	F, G, H, I	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7	polymer	12	1391.7	4	UniProt (O14733) In PDB	HOMO SAPIENS	MAP KINASE KINASE 7, MAPKK 7, JNK-ACTIVATING KINASE 2, MAPK/ERK KINASE 7, MEK 7, STRESS-ACTIVATED PROTEIN KINASE KINASE 4, SAPK KINASE 4, SAPKK-4, SAPKK4, C-JUN N-TERMINAL KINASE KINASE 2, JNK KINASE 2, JNKK 2, MKK7
3	A, B, C, D	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	4	Chemie (ANP)
4	D, H, A, B, C	SULFATE ION	non-polymer		96.1	16	Chemie (SO4)
5		water	water		18.0	276	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	173953.6
Non-Polymers*	Number of molecules	20
	Total formula weight	3561.8
All*	Total formula weight	177515.4

*Water molecules are not included.