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4UVC

LSD1(KDM1A)-CoREST in complex with 1-Phenyl-Tranylcypromine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALYSINE-SPECIFIC HISTONE DEMETHYLASE 1Apolymer87294846.21UniProt (O60341)
Pfam (PF04433)
Pfam (PF01593)
In PDB
HOMO SAPIENS (HUMAN)BRAF35-HDAC COMPLEX PROTEIN BHC110, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2
2BREST COREPRESSOR 1polymer48253102.01UniProt (Q9UKL0)
Pfam (PF01448)
Pfam (PF00249)
Pfam (PF20878)
In PDB
HOMO SAPIENS (HUMAN)PROTEIN COREST
3A[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4S)-5-[5-[(1S)-1-azanyl-1,3-diphenyl-propyl]-7,8-dimethyl-2,4-bis(oxidanylidene)-4aH-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphatenon-polymer996.91Chemie (D52)
Sequence modifications
A: -19 - 852 (UniProt: O60341)
PDBExternal DatabaseDetails
Pro 171Ala 191conflict
-Asp 390deletion
-Thr 391deletion
-Val 392deletion
-Lys 393deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight147948.2
Non-Polymers*Number of molecules1
Total formula weight996.9
All*Total formula weight148945.0
*Water molecules are not included.

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PDB entries from 2024-03-27

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