4UVB
LSD1(KDM1A)-CoREST in complex with 1-Methyl-Tranylcypromine (1S,2R)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A | polymer | 872 | 94846.2 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | HOMO SAPIENS (HUMAN) | BRAF35-HDAC COMPLEX PROTEIN BHC110, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2 |
| 2 | B (B) | REST COREPRESSOR 1 | polymer | 482 | 53102.0 | 1 | UniProt (Q9UKL0) Pfam (PF01448) Pfam (PF00249) Pfam (PF20878) | HOMO SAPIENS (HUMAN) | PROTEIN COREST |
| 3 | C (A) | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,7aS)-1-amino-1,10,11-trimethyl-4,6-dioxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate | non-polymer | 934.8 | 1 | Chemie (D51) |
Sequence modifications
A: -19 - 852 (UniProt: O60341)
| PDB | External Database | Details |
|---|---|---|
| Pro 171 | Ala 191 | conflict |
| - | Asp 390 | deletion |
| - | Thr 391 | deletion |
| - | Val 392 | deletion |
| - | Lys 393 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147948.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 934.8 | |
| All* | Total formula weight | 148883.0 |
