4UVA
LSD1(KDM1A)-CoREST in complex with 1-Methyl-Tranylcypromine (1R,2S)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A | polymer | 872 | 94846.2 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) In PDB | HOMO SAPIENS (HUMAN) | BRAF35-HDAC COMPLEX PROTEIN BHC110, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2 |
| 2 | B | REST COREPRESSOR 1 | polymer | 482 | 53102.0 | 1 | UniProt (Q9UKL0) Pfam (PF01448) Pfam (PF00249) Pfam (PF20878) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN COREST |
| 3 | A | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(4aS)-4a-[(1S,3E)-3-imino-1-phenylbutyl]-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]pentyl dihydrogen diphosphate | non-polymer | 932.8 | 1 | Chemie (D73) | |||
| 4 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: -19 - 852 (UniProt: O60341)
| PDB | External Database | Details |
|---|---|---|
| Pro 171 | Ala 191 | conflict |
| - | Asp 390 | deletion |
| - | Thr 391 | deletion |
| - | Val 392 | deletion |
| - | Lys 393 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147948.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 932.8 | |
| All* | Total formula weight | 148881.0 |
