4UV8
LSD1(KDM1A)-CoREST in complex with 1-Benzyl-Tranylcypromine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A | polymer | 872 | 94846.2 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) In PDB | HOMO SAPIENS (HUMAN) | BRAF35-HDAC COMPLEX PROTEIN BHC110, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2 |
| 2 | B | REST COREPRESSOR 1 | polymer | 482 | 53102.0 | 1 | UniProt (Q9UKL0) Pfam (PF01448) Pfam (PF00249) Pfam (PF20878) In PDB | HOMO SAPIENS (HUMAN) | PROTEIN COREST |
| 3 | A | [[(2R,3S,4S)-5-[(4aS,10aS)-4a-[(1S)-3-azanylidene-1,4-diphenyl-butyl]-7,8-dimethyl-2,4-bis(oxidanylidene)-5,10a-dihydro-1H-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentoxy]-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 1010.9 | 1 | Chemie (D69) | |||
| 4 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: -19 - 852 (UniProt: O60341)
| PDB | External Database | Details |
|---|---|---|
| Pro 171 | Ala 191 | conflict |
| - | Asp 390 | deletion |
| - | Thr 391 | deletion |
| - | Val 392 | deletion |
| - | Lys 393 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147948.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 1010.9 | |
| All* | Total formula weight | 148959.1 |
