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4UUY

Structural Identification of the Vps18 beta-propeller reveals a critical role in the HOPS complex stability and function.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
VACUOLAR MEMBRANE PROTEIN PEP3polymer34940405.32UniProt (P27801)
Pfam (PF05131)
SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)CARBOXYPEPTIDASE Y-DEFICIENT PROTEIN 3, VACUOLAR MORPHOGENESIS PROTEIN 8, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18, VACUOLAR PROTEIN-TARGETING PROTEIN 18, VPS18
2C, D, E, H, I...
(A, B)
SULFATE IONnon-polymer96.16Chemie (SO4)
3F, G, M
(A, B)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4K, L
(B)
GLYCEROLnon-polymer92.12Chemie (GOL)
5N, O
(A, B)
waterwater18.0207Chemie (HOH)
Sequence modifications
A, B: 3 - 349 (UniProt: P27801)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight80810.6
Non-Polymers*Number of molecules11
Total formula weight946.8
All*Total formula weight81757.4
*Water molecules are not included.

247035

PDB entries from 2026-01-07

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