4UUU

1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CYSTATHIONINE BETA-SYNTHASE	polymer	155	17447.2	2	UniProt (P35520) Pfam (PF00571) In PDB	HOMO SAPIENS (HUMAN)
2	A, B	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
3	A, B	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
4		water	water		18.0	157	Chemie (HOH)

Sequence modifications

A, B: 406 - 515 (UniProt: P35520)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Met -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34894.3
Non-Polymers*	Number of molecules	14
	Total formula weight	1541.7
All*	Total formula weight	36436.0

*Water molecules are not included.