4UTR

Crystal structure of zebrafish Sirtuin 5 in complex with glutarylated CPS1-peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL	polymer	275	30423.8	2	UniProt (Q6DHI5) Pfam (PF02146) In PDB	DANIO RERIO (ZEBRAFISH)
2	C	GLUTARYL-CPS1 PEPTIDE	polymer	9	969.1	1	UniProt (Q5R209) UniProt (by SIFTS) (P31327) In PDB	HOMO SAPIENS	3-NITRO-PROPIONYL-CPS1 PEPTIDE
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	A, B	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5	B	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
6	B	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7	C	GLUTARIC ACID	non-polymer		132.1	1	Chemie (GUA)
8		water	water		18.0	57	Chemie (HOH)

Sequence modifications

A, B: 30 - 298 (UniProt: Q6DHI5)

PDB	External Database	Details
Gly 24	-	expression tag
Ile 25	-	expression tag
Asp 26	-	expression tag
Pro 27	-	expression tag
Phe 28	-	expression tag
Thr 29	-	expression tag

C: 1 - 8 (UniProt: Q5R209)

PDB	External Database	Details
Bez 0	-	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	61816.7
Non-Polymers*	Number of molecules	8
	Total formula weight	550.3
All*	Total formula weight	62366.9

*Water molecules are not included.