4URZ
The crystal structure of H-Ras and SOS in complex with ligands
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | GTPASE HRAS | polymer | 185 | 21083.6 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | HOMO SAPIENS (HUMAN) | H-RAS-1, HA-RAS, TRANSFORMING PROTEIN P21, C-H-RAS, P21RAS, H-RAS |
2 | S | SON OF SEVENLESS HOMOLOG 1 | polymer | 487 | 57177.4 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) In PDB | HOMO SAPIENS (HUMAN) | SOS-1, SON OF SEVENLESS-1 |
3 | R | 1-[(4-aminophenyl)sulfonyl]piperidin-2-one | non-polymer | 254.3 | 1 | Chemie (VJP) | |||
4 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
R: 1 - 166 (UniProt: P01112)
S: 564 - 1049 (UniProt: Q07889)
PDB | External Database | Details |
---|---|---|
Met -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
Gly -11 | - | expression tag |
Gly -10 | - | expression tag |
Gly -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 563 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 78261.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 254.3 | |
All* | Total formula weight | 78515.3 |