4URK
PI3Kg in complex with AZD6482
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | polymer | 966 | 110727.1 | 1 | UniProt (P48736) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | HOMO SAPIENS (HUMAN) | PHOSPHOINOSITIDE 3-KINASE GAMMA, PI3-KINASE SUBUNIT GAMMA, PI3K-GAMMA, PI3KGAMMA, PTDINS-3-KINASE SUBUNIT GAMMA, 2.7.1.153, PHOSPHATIDYLINOSITOL 4\,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT GAMMA, PTDINS-3-KINASE SUBUNIT P110-GAMMA, P110GAMMA, PHOSPHOINOSITIDE-3-KINASE CATALYTIC GAMMA POLYPEPTIDE, SERINE/THREONINE PROTEIN KINASE PIK3CG, P120-PI3K |
| 2 | A | 2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid | non-polymer | 408.4 | 1 | Chemie (A82) |
Sequence modifications
A: 144 - 1102 (UniProt: P48736)
| PDB | External Database | Details |
|---|---|---|
| Met 143 | - | expression tag |
| His 1103 | - | expression tag |
| His 1104 | - | expression tag |
| His 1105 | - | expression tag |
| His 1106 | - | expression tag |
| His 1107 | - | expression tag |
| His 1108 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 110727.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 408.4 | |
| All* | Total formula weight | 111135.6 |
