4UP1
Crystal structure of native human Thymidylate synthase in active form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | THYMIDYLATE SYNTHASE | polymer | 313 | 35779.0 | 4 | UniProt (P04818) Pfam (PF00303) | HOMO SAPIENS (HUMAN) | TS, TSASE |
| 2 | E, F, G, H, I... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) |
Sequence modifications
A, B, C, D: 1 - 313 (UniProt: P04818)
| PDB | External Database | Details |
|---|---|---|
| Leu 2 | Pro 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 143115.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1152.8 | |
| All* | Total formula weight | 144268.7 |
