4UMB
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | polymer | 351 | 38712.1 | 4 | UniProt (Q9K169) Pfam (PF00793) | NEISSERIA MENINGITIDIS | 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE, DAHP SYNTHASE, PHOSPHO-2-KETO-3-DEOXYHEPTONATE ALDOLASE |
| 2 | E, H, K, N (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | F, J, M, P (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 4 | G, I, L, O (A, B, C, D) | (2R)-2-(phosphonooxy)propanoic acid | non-polymer | 170.1 | 4 | Chemie (0V5) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 633 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 154848.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1279.9 | |
| All* | Total formula weight | 156128.4 |
