4UJ4

Crystal structure of human Rab11-Rabin8-FIP3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	Ras-related protein Rab-11A	polymer	185	20958.6	4	UniProt (P62491) Pfam (PF00071)	Homo sapiens (Human)	Rab-11,YL8, RAB11A
2	B, E, H, K (B, E, H, K)	Rab-3A-interacting protein	polymer	195	22217.5	4	UniProt (Q96QF0)	Homo sapiens (Human)	Rab3A-interacting protein,Rabin-3,SSX2-interacting protein
3	C, F, I, L (C, F, I, L)	Rab11 family-interacting protein 3	polymer	66	7269.2	4	UniProt (O75154) Pfam (PF09457)	Homo sapiens (Human)	Rab11-FIP3,Arfophilin-1,EF hands-containing Rab-interacting protein,Eferin,MU-MB-17.148
4	M, O, Q, S (A, D, G, J)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	4	Chemie (GNP)
5	N, P, R, T (A, D, G, J)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Sequence modifications

A, D, G, J: 4 - 186 (UniProt: P62491)

PDB	External Database	Details
Gly 2	-	expression tag
Ala 3	-	expression tag
Leu 70	Gln 70	engineered mutation

B, E, H, K: 270 - 460 (UniProt: Q96QF0)

PDB	External Database	Details
Gly 266	-	expression tag
Ala 267	-	expression tag
Ala 268	-	expression tag
Ser 269	-	expression tag

C, F, I, L: 695 - 756 (UniProt: O75154)

PDB	External Database	Details
Gly 691	-	expression tag
Ala 692	-	expression tag
Ala 693	-	expression tag
Ser 694	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	201780.9
Non-Polymers*	Number of molecules	8
	Total formula weight	2186.0
All*	Total formula weight	203967.0

*Water molecules are not included.