4UJ4

Crystal structure of human Rab11-Rabin8-FIP3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0005085	molecular_function	guanyl-nucleotide exchange factor activity
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
E	0005085	molecular_function	guanyl-nucleotide exchange factor activity
G	0003924	molecular_function	GTPase activity
G	0005525	molecular_function	GTP binding
H	0005085	molecular_function	guanyl-nucleotide exchange factor activity
J	0003924	molecular_function	GTPase activity
J	0005525	molecular_function	GTP binding
K	0005085	molecular_function	guanyl-nucleotide exchange factor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GNP A 200

Chain	Residue
A	SER20
A	LEU38
A	SER40
A	SER42
A	THR43
A	GLY69
A	ASN124
A	LYS125
A	ASP127
A	LEU128
A	SER154
A	GLY21
A	ALA155
A	LEU156
A	MG201
B	TYR423
A	VAL22
A	GLY23
A	LYS24
A	SER25
A	ASN26
A	PHE36
A	ASN37

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 201

Chain	Residue
A	SER25
A	THR43
A	GNP200

---

site_id	AC3
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GNP D 200

Chain	Residue
D	SER20
D	GLY21
D	VAL22
D	GLY23
D	LYS24
D	SER25
D	ASN26
D	PHE36
D	ASN37
D	LEU38
D	SER40
D	SER42
D	THR43
D	THR67
D	GLY69
D	ASN124
D	LYS125
D	ASP127
D	LEU128
D	SER154
D	ALA155
D	LEU156
D	MG201
E	TYR423

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 201

Chain	Residue
D	SER25
D	THR43
D	ASP66
D	GNP200

---

site_id	AC5
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GNP G 200

Chain	Residue
G	SER20
G	GLY21
G	GLY23
G	LYS24
G	SER25
G	ASN26
G	ASN37
G	LEU38
G	SER40
G	SER42
G	THR43
G	GLY69
G	ASN124
G	LYS125
G	ASP127
G	LEU128
G	SER154
G	ALA155
G	LEU156
G	MG201
H	TYR423

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG G 201

Chain	Residue
G	SER25
G	THR43
G	ASP66
G	THR67
G	GNP200

---

site_id	AC7
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GNP J 200

Chain	Residue
J	ALA155
J	LEU156
J	MG201
K	TYR423
J	SER20
J	GLY21
J	VAL22
J	GLY23
J	LYS24
J	SER25
J	ASN26
J	PHE36
J	ASN37
J	LEU38
J	SER40
J	SER42
J	THR43
J	GLY69
J	ASN124
J	LYS125
J	ASP127
J	LEU128
J	SER154

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG J 201

Chain	Residue
J	SER25
J	THR43
J	ASP66
J	THR67
J	GNP200

---

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. KEEL

Chain	Residue	Details
B	LYS457-LEU460

---

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL

Chain	Residue	Details
A	VAL14-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER272
J	GLY18
J	ASN124
J	SER154
E	SER272
H	SER272
K	SER272
D	ASN124
D	SER154
G	GLY18
G	ASN124
G	SER154

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q68EF0

Chain	Residue	Details
B	SER280
E	SER280
H	SER280
K	SER280

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:1OIW, ECO:0007744|PDB:4D0L, ECO:0007744|PDB:4D0M, ECO:0007744|PDB:5C46, ECO:0007744|PDB:5FBL

Chain	Residue	Details
A	ASP66
D	ASP66
G	ASP66
J	ASP66

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32974215

Chain	Residue	Details
A	ARG4
D	ARG4
G	ARG4
J	ARG4

---