4UJ3

Crystal structure of human Rab11-Rabin8-FIP3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J, M...	RAS-RELATED PROTEIN RAB-11A	polymer	187	21116.7	8	UniProt (P62491) Pfam (PF00071) In PDB	HOMO SAPIENS (HUMAN)	RAB-11, YL8, RAB11A
2	B, E, H, K, N...	RAB-3A-INTERACTING PROTEIN	polymer	195	22217.5	8	UniProt (Q96QF0) In PDB	HOMO SAPIENS (HUMAN)	RAB3A-INTERACTING PROTEIN, RABIN-3, SSX2-INTERACTING PROTEIN, RABIN8
3	C, F, I, L, O...	RAB11 FAMILY-INTERACTING PROTEIN 3	polymer	66	7269.2	8	UniProt (O75154) Pfam (PF09457) In PDB	HOMO SAPIENS (HUMAN)	FIP3-RAB11, RAB11-FIP3, ARFOPHILIN-1, EF HANDS-CONTAINING RAB-INTERACTING PROTEIN, EFERIN, MU-MB-17.148, FIP3
4	D, G, J, M, P...	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	8	Chemie (GNP)
5	D, G, J, M, P...	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
6	M	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	V	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
8		water	water		18.0	108	Chemie (HOH)

Sequence modifications

A, D, G, J, M, P, S, V: 4 - 186 (UniProt: P62491)

PDB	External Database	Details
Gly 0	-	expression tag
Ala 1	-	expression tag
Ala 2	-	expression tag
Ser 3	-	expression tag
Leu 70	Gln 70	engineered mutation

B, E, H, K, N, Q, T, W: 270 - 460 (UniProt: Q96QF0)

PDB	External Database	Details
Gly 266	-	expression tag
Ala 267	-	expression tag
Ala 268	-	expression tag
Ser 269	-	expression tag

C, F, I, L, O, R, U, X: 695 - 756 (UniProt: O75154)

PDB	External Database	Details
Gly 691	-	expression tag
Ala 692	-	expression tag
Ala 693	-	expression tag
Ser 694	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	404827.2
Non-Polymers*	Number of molecules	18
	Total formula weight	4662.3
All*	Total formula weight	409489.5

*Water molecules are not included.