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4UIH

Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAINpolymer49554363.73UniProt (P14340)
Pfam (PF00869)
Pfam (PF02832)
Pfam (PF21659)
DENGUE VIRUS 2 (ASIAN TIGER MOSQUITO)
2D, F
(D, F)
ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAINpolymer12813805.52HOMO SAPIENS (HUMAN)
3E, G
(E, G)
ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAINpolymer11512090.32HOMO SAPIENS (HUMAN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight214882.7
All*Total formula weight214882.7
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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