4UHZ

Crystal structure of the human RGMB-BMP2 complex, crystal form 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	BONE MORPHOGENETIC PROTEIN 2	polymer	114	12923.9	1	UniProt (P12643) Pfam (PF00019) In PDB	HOMO SAPIENS (HUMAN)	BMP-2, BONE MORPHOGENETIC PROTEIN 2A, BMP-2A, BMP2
2	B	RGM DOMAIN FAMILY MEMBER B	polymer	96	10532.7	1	UniProt (Q6NW40) Pfam (PF06535) In PDB	HOMO SAPIENS (HUMAN)	DRG11-RESPONSIVE AXONAL GUIDANCE AND OUTGROWTH OF NEURITE, DRAGON, REPULSIVE GUIDANCE MOLECULE B, RGMB
3	A, B	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)

Sequence modifications

B: 52 - 137 (UniProt: Q6NW40)

PDB	External Database	Details
Glu 50	-	expression tag
Thr 51	-	expression tag
Thr 138	-	expression tag
Lys 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23456.6
Non-Polymers*	Number of molecules	8
	Total formula weight	768.5
All*	Total formula weight	24225.1

*Water molecules are not included.