4UED

Complex of human eIF4E with the 4E binding protein 4E-BP1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	polymer	186	21657.6	1	UniProt (P06730) Pfam (PF01652)	HOMO SAPIENS (HUMAN)	EIF4E, EIF-4F 25 KDA SUBUNIT, MRNA CAP-BINDING PROTEIN
2	B (B)	EUKARYOTIC TRANSLATION FACTOR 4E-BINDING PROTEIN 1	polymer	38	4333.1	1	UniProt (Q13541)	HOMO SAPIENS (HUMAN)	4E-BP1, EIF4E-BINDING PROTEIN 1, PHOSPHORYLATED HEAT- AND ACID-STABLE PROTEIN REGULATED BY INSULIN 1, PHAS-I
3	C, D (A, B)	water	water		18.0	119	Chemie (HOH)

Sequence modifications

A: 36 - 217 (UniProt: P06730)

PDB	External Database	Details
Gly 32	-	expression tag
Pro 33	-	expression tag
His 34	-	expression tag
Met 35	-	expression tag

B: 50 - 83 (UniProt: Q13541)

PDB	External Database	Details
Gly 46	-	expression tag
Pro 47	-	expression tag
His 48	-	expression tag
Met 49	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25990.7
All*	Total formula weight	25990.7

*Water molecules are not included.