4UE7
Thrombin in complex with 1-amidinopiperidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | THROMBIN HEAVY CHAIN | polymer | 258 | 29651.1 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | PROTHROMBIN, COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2, THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN |
| 2 | B (I) | HIRUDIN VARIANT-2 | polymer | 12 | 1548.6 | 1 | UniProt (P09945) | HIRUDO MEDICINALIS | |
| 3 | C (L) | THROMBIN LIGHT CHAIN | polymer | 28 | 3317.7 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | PROTHROMBIN, COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2 |
| 4 | D (H) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) | |||
| 5 | E, F, G (H) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H, I (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | J (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 8 | K, L, N (H) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 9 | M (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 10 | O (H) | piperidine-1-carboximidamide | non-polymer | 127.2 | 1 | Chemie (MRZ) | |||
| 11 | P (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 12 | Q, R, S (H, I, L) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34517.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1189.0 | |
| All* | Total formula weight | 35706.4 |
