4UBF

HsMCAK motor domain complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Kinesin-like protein KIF2C	polymer	387	43295.6	4	UniProt (Q99661) Pfam (PF00225)	Homo sapiens (Human)	Kinesin-like protein 6,Mitotic centromere-associated kinesin,MCAK
2	E (P)	Kinesin-like protein KIF2C	polymer	12	1376.5	1	UniProt (Q99661)	Homo sapiens (Human)	Kinesin-like protein 6,Mitotic centromere-associated kinesin,MCAK
3	F, H, J, K, L... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)	Homo sapiens (Human)
4	G, I, M, P (A, B, C, D)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	4	Chemie (ADP)
5	Q, R, S, T, U (A, B, C, D, P)	water	water		18.0	69	Chemie (HOH)

Sequence modifications

A, B, C, D: 225 - 593 (UniProt: Q99661)

PDB	External Database	Details
Met 207	-	expression tag
Gly 208	-	expression tag
Ser 209	-	expression tag
Ser 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
Ser 217	-	expression tag
Ser 218	-	expression tag
Gly 219	-	expression tag
Leu 220	-	expression tag
Val 221	-	expression tag
Pro 222	-	expression tag
Arg 223	-	expression tag
Gly 224	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	174558.9
Non-Polymers*	Number of molecules	11
	Total formula weight	1878.9
All*	Total formula weight	176437.8

*Water molecules are not included.