4UAO

Crystal structure of Apical Membrane Antigen 1 from Plasmodium Knowlesi in complex with an invasion inhibitory antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Apical merozoite antigen 1	polymer	370	42511.4	1	UniProt (B3L5E1) Pfam (PF02430) UniProt (by SIFTS) (A0A384KGX8) In PDB	Plasmodium knowlesi
2	B	immunoglobulin R31C2 light chain	polymer	214	23671.4	1	Pfam (PF07654) UniProt (by SIFTS) (P01835) In PDB	Rattus norvegicus (Norway Rat)
3	C	immunoglobulin R31C2 VH and CH1 regions	polymer	223	23967.8	1	Pfam (PF07654) UniProt (by SIFTS) (P20760) In PDB	Rattus norvegicus (Norway Rat)

Sequence modifications

A: 43 - 387 (UniProt: B3L5E1)

PDB	External Database	Details
Glu 41	-	cloning artifact
Phe 42	-	cloning artifact
Lys 107	Asn 107	engineered mutation
Asn 178	Ser 178	engineered mutation
Glu 189	Asn 189	engineered mutation
Arg 240	Ser 240	engineered mutation
Gly 388	-	cloning artifact
Leu 389	-	expression tag
Glu 390	-	expression tag
Gln 391	-	expression tag
Lys 392	-	expression tag
Leu 393	-	expression tag
Ile 394	-	expression tag
Ser 395	-	expression tag
Glu 396	-	expression tag
Glu 397	-	expression tag
Asp 398	-	expression tag
Leu 399	-	expression tag
Asn 400	-	expression tag
Ser 401	-	expression tag
Ala 402	-	expression tag
Val 403	-	expression tag
Asp 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	90150.6
All*	Total formula weight	90150.6

*Water molecules are not included.