4UAF

Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Importin subunit alpha-1	polymer	466	50461.3	1	UniProt (P52293) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186) In PDB	Mus musculus (Mouse)	Importin alpha P1,Karyopherin subunit alpha-2,Pendulin,Pore targeting complex 58 kDa subunit,PTAC58,RAG cohort protein 1,SRP1-alpha
2	E	Polymerase basic protein 2	polymer	87	9339.7	1	UniProt (P31345) Pfam (PF20952) In PDB	Influenza A virus	RNA-directed RNA polymerase subunit P3
3	B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4		water	water		18.0	470	Chemie (HOH)

Sequence modifications

B: 69 - 529 (UniProt: P52293)

PDB	External Database	Details
Met 64	-	initiating methionine
Ala 65	-	expression tag
Asp 66	-	expression tag
Ile 67	-	expression tag
Gly 68	-	expression tag
Ser 69	Asn 69	engineered mutation

E: 678 - 759 (UniProt: P31345)

PDB	External Database	Details
Gly 673	-	expression tag
Pro 674	-	expression tag
Leu 675	-	expression tag
Gly 676	-	expression tag
Ser 677	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59800.9
Non-Polymers*	Number of molecules	2
	Total formula weight	189.9
All*	Total formula weight	59990.9

*Water molecules are not included.