4U6W
HsMetAP (F220M) in complex with 1-amino-2-propylpentyl]phosphonic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Methionine aminopeptidase 1 | polymer | 306 | 34438.2 | 1 | UniProt (P53582) Pfam (PF00557) In PDB | Homo sapiens (Human) | MetAP 1,Peptidase M 1 |
| 2 | A | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | A | [(1R)-1-amino-2-propylpentyl]phosphonic acid | non-polymer | 209.2 | 1 | Chemie (Q08) | |||
| 6 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A: 90 - 395 (UniProt: P53582)
| PDB | External Database | Details |
|---|---|---|
| Met 309 | Phe 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34438.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 458.3 | |
| All* | Total formula weight | 34896.5 |
