4U3Z
APO MAP4K4 T181E Phosphomimetic Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Mitogen-activated protein kinase kinase kinase kinase 4 | polymer | 332 | 37898.1 | 2 | UniProt (O95819) Pfam (PF00069) | Homo sapiens (Human) | HPK/GCK-like kinase HGK,MAPK/ERK kinase kinase kinase 4,MEKKK 4,Nck-interacting kinase |
| 2 | C, D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 3 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | F, G (B, A) | water | water | 18.0 | 411 | Chemie (HOH) |
Sequence modifications
B, A: 2 - 328 (UniProt: O95819)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Glu 181 | Thr 181 | engineered mutation |
| Gly 329 | - | expression tag |
| Asn 330 | - | expression tag |
| Ser 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75796.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 413.5 | |
| All* | Total formula weight | 76209.6 |
