4U30
Human mesotrypsin complexed with bikunin Kunitz domain 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Trypsin-3 | polymer | 224 | 24257.5 | 4 | UniProt (P35030) Pfam (PF00089) | Homo sapiens (Human) | Brain trypsinogen,Mesotrypsinogen,Serine protease 3,Serine protease 4,Trypsin III,Trypsin IV |
| 2 | E, F, G, H (X, Y, Z, W) | Trypstatin | polymer | 59 | 6454.5 | 4 | UniProt (P02760) Pfam (PF00014) | Homo sapiens (Human) | |
| 3 | I, J, K, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, X...) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 16 - 246 (UniProt: P35030)
X, Y, Z, W: 1 - 58 (UniProt: P02760)
| PDB | External Database | Details |
|---|---|---|
| Ala 127 | Thr 188 | variant |
| Ala 195 | Ser 257 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 122847.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 123008.2 |
