4U2K
X-ray structure uridine phosphorylase from Vibrio cholerae in complex with anticancer compound at 2.13 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Uridine phosphorylase | polymer | 253 | 27109.0 | 6 | UniProt (Q9K4U1) Pfam (PF01048) | Vibrio cholerae | |
| 2 | G, H, I, K, L... (A, B, C, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 3 | J, P (B, D) | 1-[(2R)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione | non-polymer | 202.2 | 2 | Chemie (4WR) | |||
| 4 | M, Q (D, E) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | N (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | O, U (D, F) | 1-[(2S)-2,3-diaminopropyl]-5-fluoropyrimidine-2,4(1H,3H)-dione | non-polymer | 202.2 | 2 | Chemie (M5F) | |||
| 7 | T (F) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 8 | AA, V, W, X, Y... (F, A, B, C, D...) | water | water | 18.0 | 592 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 162654.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1655.7 | |
| All* | Total formula weight | 164309.6 |
