4U27
Crystal structure of the E. coli ribosome bound to flopristin and linopristin.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, CB (AA, CA) | 16S rRNA | polymer | 1539 | 498725.4 | 2 | GenBank (359330873) | Escherichia coli str. K-12 substr. MDS42 | |
| 2 | B, DB (AB, CB) | 30S ribosomal protein S2 | polymer | 218 | 24253.9 | 2 | UniProt (P0A7V0) Pfam (PF00318) | Escherichia coli | |
| 3 | C, EB (AC, CC) | 30S ribosomal protein S3 | polymer | 206 | 23078.8 | 2 | UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189) | Escherichia coli | |
| 4 | D, FB (AD, CD) | 30S ribosomal protein S4 | polymer | 205 | 23383.0 | 2 | UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479) | Escherichia coli | |
| 5 | E, GB (AE, CE) | 30S ribosomal protein S5 | polymer | 150 | 15804.3 | 2 | UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719) | Escherichia coli | |
| 6 | F, HB (AF, CF) | 30S ribosomal protein S6 | polymer | 100 | 11669.4 | 2 | UniProt (P02358) Pfam (PF01250) | Escherichia coli | |
| 7 | G, IB (AG, CG) | 30S ribosomal protein S7 | polymer | 151 | 16861.5 | 2 | UniProt (P02359) Pfam (PF00177) | Escherichia coli | |
| 8 | H, JB (AH, CH) | 30S ribosomal protein S8 | polymer | 129 | 14015.4 | 2 | UniProt (P0A7W7) Pfam (PF00410) | Escherichia coli | |
| 9 | I, KB (AI, CI) | 30S ribosomal protein S9 | polymer | 127 | 14554.9 | 2 | UniProt (P0A7X3) Pfam (PF00380) | Escherichia coli | |
| 10 | J, LB (AJ, CJ) | 30S ribosomal protein S10 | polymer | 98 | 11197.0 | 2 | UniProt (P0A7R5) Pfam (PF00338) | Escherichia coli | |
| 11 | K, MB (AK, CK) | 30S ribosomal protein S11 | polymer | 117 | 12487.2 | 2 | UniProt (P0A7R9) Pfam (PF00411) | Escherichia coli | |
| 12 | L, NB (AL, CL) | 30S ribosomal protein S12 | polymer | 123 | 13637.0 | 2 | UniProt (P0A7S3) Pfam (PF00164) | Escherichia coli | |
| 13 | M, OB (AM, CM) | 30S ribosomal protein S13 | polymer | 114 | 12625.8 | 2 | UniProt (P0A7S9) Pfam (PF00416) | Escherichia coli | |
| 14 | N, PB (AN, CN) | 30S ribosomal protein S14 | polymer | 100 | 11475.4 | 2 | UniProt (P0AG59) Pfam (PF00253) | Escherichia coli | |
| 15 | O, QB (AO, CO) | 30S ribosomal protein S15 | polymer | 88 | 10159.6 | 2 | UniProt (P0ADZ4) Pfam (PF00312) | Escherichia coli | |
| 16 | P, RB (AP, CP) | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 2 | UniProt (P0A7T3) Pfam (PF00886) | Escherichia coli | |
| 17 | Q, SB (AQ, CQ) | 30S ribosomal protein S17 | polymer | 80 | 9263.9 | 2 | UniProt (P0AG63) Pfam (PF00366) | Escherichia coli | |
| 18 | R, TB (AR, CR) | 30S ribosomal protein S18 | polymer | 55 | 6466.5 | 2 | UniProt (P0A7T7) Pfam (PF01084) | Escherichia coli | |
| 19 | S, UB (AS, CS) | 30S ribosomal protein S19 | polymer | 79 | 9057.6 | 2 | UniProt (P0A7U3) Pfam (PF00203) | Escherichia coli | |
| 20 | T, VB (AT, CT) | 30S ribosomal protein S20 | polymer | 85 | 9506.2 | 2 | UniProt (P0A7U7) Pfam (PF01649) | Escherichia coli | |
| 21 | U, WB (AU, CU) | 30S ribosomal protein S21 | polymer | 51 | 6067.1 | 2 | UniProt (P68679) Pfam (PF01165) | Escherichia coli | |
| 22 | V, XB (BA, DA) | 23S rRNA | polymer | 2903 | 941306.2 | 2 | GenBank (359330873) | Escherichia coli str. K-12 substr. MDS42 | |
| 23 | W, YB (BB, DB) | 5S rRNA | polymer | 119 | 38483.9 | 2 | GenBank (359330873) | Escherichia coli str. K-12 substr. MDS42 | |
| 24 | X, ZB (BC, DC) | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 2 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli | |
| 25 | AC, Y (BD, DD) | 50S ribosomal protein L3 | polymer | 209 | 22277.5 | 2 | UniProt (P60438) Pfam (PF00297) | Escherichia coli | |
| 26 | BC, Z (BE, DE) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 2 | UniProt (P60723) Pfam (PF00573) | Escherichia coli | |
| 27 | AA, CC (BF, DF) | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 2 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) | Escherichia coli | |
| 28 | BA, DC (BG, DG) | 50S ribosomal protein L6 | polymer | 176 | 18801.6 | 2 | UniProt (P0AG55) Pfam (PF00347) | Escherichia coli | |
| 29 | CA, EC (BH, DH) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 2 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) | Escherichia coli | |
| 30 | DA, FC (BI, DI) | 50S ribosomal protein L11 | polymer | 141 | 14763.2 | 2 | UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298) | Escherichia coli | |
| 31 | EA, GC (BJ, DJ) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 2 | UniProt (P0AA10) Pfam (PF00572) | Escherichia coli | |
| 32 | FA, HC (BK, DK) | 50S ribosomal protein L14 | polymer | 122 | 13451.9 | 2 | UniProt (P0ADY3) Pfam (PF00238) | Escherichia coli | |
| 33 | GA, IC (BL, DL) | 50S ribosomal protein L15 | polymer | 143 | 14877.3 | 2 | UniProt (P02413) Pfam (PF00828) | Escherichia coli | |
| 34 | HA, JC (BM, DM) | 50S ribosomal protein L16 | polymer | 136 | 15312.3 | 2 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli | |
| 35 | IA, KC (BN, DN) | 50S ribosomal protein L17 | polymer | 120 | 13721.9 | 2 | UniProt (P0AG44) Pfam (PF01196) | Escherichia coli | |
| 36 | JA, LC (BO, DO) | 50S ribosomal protein L18 | polymer | 116 | 12663.5 | 2 | UniProt (P0C018) Pfam (PF00861) | Escherichia coli | |
| 37 | KA, MC (BP, DP) | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 2 | UniProt (P0A7K6) Pfam (PF01245) | Escherichia coli | |
| 38 | LA, NC (BQ, DQ) | 50S ribosomal protein L20 | polymer | 117 | 13396.8 | 2 | UniProt (P0A7L3) Pfam (PF00453) | Escherichia coli | |
| 39 | MA, OC (BR, DR) | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 2 | UniProt (P0AG48) Pfam (PF00829) | Escherichia coli | |
| 40 | NA, PC (BS, DS) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 2 | UniProt (P61175) Pfam (PF00237) | Escherichia coli | |
| 41 | OA, QC (BT, DT) | 50S ribosomal protein L23 | polymer | 93 | 10546.5 | 2 | UniProt (P0ADZ0) Pfam (PF00276) | Escherichia coli | |
| 42 | PA, RC (BU, DU) | 50S ribosomal protein L24 | polymer | 102 | 11078.9 | 2 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) | Escherichia coli | |
| 43 | QA, SC (BV, DV) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 2 | UniProt (P68919) Pfam (PF01386) | Escherichia coli | |
| 44 | RA, TC (BW, DW) | 50S ribosomal protein L27 | polymer | 76 | 8275.5 | 2 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli | |
| 45 | SA, UC (BX, DX) | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 2 | UniProt (P0A7M2) Pfam (PF00830) | Escherichia coli | |
| 46 | TA, VC (BY, DY) | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 2 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli | |
| 47 | UA, WC (BZ, DZ) | 50S ribosomal protein L30 | polymer | 58 | 6423.6 | 2 | UniProt (P0AG51) Pfam (PF00327) | Escherichia coli | |
| 48 | VA, XC (B0, D0) | 50S ribosomal protein L32 | polymer | 56 | 6332.2 | 2 | UniProt (P0A7N4) Pfam (PF01783) | Escherichia coli | |
| 49 | WA, YC (B1, D1) | 50S ribosomal protein L33 | polymer | 50 | 5814.8 | 2 | UniProt (P0A7N9) Pfam (PF00471) | Escherichia coli | |
| 50 | XA, ZC (B2, D2) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 2 | UniProt (P0A7P5) Pfam (PF00468) | Escherichia coli | |
| 51 | AD, YA (B3, D3) | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 2 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli | Ribosomal protein A |
| 52 | BD, ZA (B4, D4) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 2 | UniProt (P0A7Q6) Pfam (PF00444) | Escherichia coli | Ribosomal protein B |
| 53 | AB (B5) | 50S ribosomal protein L1 | polymer | 228 | 24741.5 | 1 | UniProt (Q5SLP7) Pfam (PF00687) | Thermus thermophilus | |
| 54 | BB, CD (B6, D6) | Linopristin | polymer | 7 | 968.1 | 2 | BIRD (PRD_002101) | synthetic construct | |
| 55 | AE, AF, AG, AH, AI... (AA, BA, CA, DA, DB...) | MAGNESIUM ION | non-polymer | 24.3 | 498 | Chemie (MG) | |||
| 56 | UP, XF (DA, BA) | Flopristin | non-polymer | 531.6 | 2 | Chemie (VIF) | |||
| 57 | KW, PN (D4, B4) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 58 | AX, BX, CX, DX, EX... (BT, B2, B3, B4, CA...) | water | water | 18.0 | 1723 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 107 |
| Total formula weight | 4257564.6 | |
| Non-Polymers* | Number of molecules | 502 |
| Total formula weight | 13297.9 | |
| All* | Total formula weight | 4270862.6 |
