4U1X
Full length GluA2-kainate-(R,R)-2b complex crystal form B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 2 | polymer | 824 | 92574.7 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, G, J, L (A, B, C, D) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 4 | Chemie (KAI) PubChem (23616889) PubChem (45039619) PubChem (101994997) PubChem (135037246) PubChem (6603893) PubChem (3816) PubChem (10255) PubChem (73345) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6453379) PubChem (6604705) PubChem (10036135) PubChem (11095940) | |||
| 3 | F, H, K, M (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | I, O (B, D) | N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | non-polymer | 480.7 | 2 | Chemie (FWF) PubChem (22259901) PubChem (44468130) PubChem (44468131) | |||
| 5 | N (D) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) PubChem (4478249) |
Sequence modifications
A, B, C, D: 8 - 826 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Glu 239 | Asn 256 | engineered mutation |
| - | Leu 402 | deletion |
| - | Pro 403 | deletion |
| - | Ser 404 | deletion |
| - | Gly 405 | deletion |
| Asp 385 | Asn 406 | engineered mutation |
| Gln 392 | Asn 413 | engineered mutation |
| Ala 528 | Cys 549 | engineered mutation |
| Leu 535 | Gly 556 | engineered mutation |
| Phe 577 | Leu 598 | engineered mutation |
| Ala 580 | Ser 601 | engineered mutation |
| Lys 582 | Gly 603 | engineered mutation |
| Leu 583 | Ala 604 | engineered mutation |
| Phe 585 | Met 606 | engineered mutation |
| Ala 589 | Cys 610 | engineered mutation |
| Ala 598 | Gly 619 | engineered mutation |
| Ala 602 | Gly 623 | engineered mutation |
| Ala 815 | Cys 836 | engineered mutation |
| Gly 827 | - | expression tag |
| Leu 828 | - | expression tag |
| Val 829 | - | expression tag |
| Pro 830 | - | expression tag |
| Arg 831 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 370298.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2894.4 | |
| All* | Total formula weight | 373193.2 |
