4U1C

Crystal structure of the eIF3a/eIF3c PCI-domain heterodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	Eukaryotic translation initiation factor 3 subunit C	polymer	567	65808.0	1	UniProt (P32497) Pfam (PF05470) Pfam (PF01399) In PDB	Saccharomyces cerevisiae (Baker's yeast)	eIF3c,Eukaryotic translation initiation factor 3 93 kDa subunit,eIF3 p93,Nuclear transport protein NIP1,Translation initiation factor eIF3,p93 subunit
2	A	Eukaryotic translation initiation factor 3 subunit A	polymer	274	31683.0	1	UniProt (P38249) Pfam (PF22591) In PDB	Saccharomyces cerevisiae (Baker's yeast)	eIF3a,Eukaryotic translation initiation factor 3 110 kDa subunit homolog,eIF3 p110,Translation initiation factor eIF3,p110 subunit homolog

Sequence modifications

C: 247 - 812 (UniProt: P32497)

PDB	External Database	Details
Met 246	-	initiating methionine

A: 225 - 495 (UniProt: P38249)

PDB	External Database	Details
Ser 222	-	expression tag
Asn 223	-	expression tag
Ala 224	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97491.0
All*	Total formula weight	97491.0

*Water molecules are not included.