4TYH
Ternary complex of P38 and MK2 with a P38 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MAP kinase-activated protein kinase 2 | polymer | 350 | 40385.8 | 1 | UniProt (P49137) Pfam (PF00069) | Homo sapiens (Human) | MK2 |
| 2 | B (B) | Mitogen-activated protein kinase 14 | polymer | 348 | 39856.6 | 1 | UniProt (P47811) Pfam (PF00069) | Mus musculus (Mouse) | MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha |
| 3 | C (B) | N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | non-polymer | 426.5 | 1 | Chemie (39G) | |||
| 4 | D (B) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80242.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 426.5 | |
| All* | Total formula weight | 80669.0 |
