4TXR

Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM and CHMP5 MIM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Charged multivesicular body protein 1b	polymer	25	2719.0	1	UniProt (Q7LBR1) In PDB	Homo sapiens (Human)	CHMP1.5,Chromatin-modifying protein 1b,CHMP1b,Vacuolar protein sorting-associated protein 46-2,hVps46-2
2	A	Vacuolar protein sorting-associated protein VTA1 homolog	polymer	163	18792.7	1	UniProt (Q9NP79) Pfam (PF04652) In PDB	Homo sapiens (Human)	Dopamine-responsive gene 1 protein,DRG-1,LYST-interacting protein 5,LIP5,SKD1-binding protein 1,SBP1
3	C	Charged multivesicular body protein 5	polymer	58	6188.4	1	UniProt (Q9NZZ3) Pfam (PF03357) In PDB	Homo sapiens (Human)	Chromatin-modifying protein 5,SNF7 domain-containing protein 2,Vacuolar protein sorting-associated protein 60,hVps60
4	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	A, C	1,2-ETHANEDIOL	non-polymer		62.1	9	Chemie (EDO)
6		water	water		18.0	279	Chemie (HOH)

Sequence modifications

B: 176 - 199 (UniProt: Q7LBR1)

PDB	External Database	Details
Ser 175	-	expression tag

A: 1 - 162 (UniProt: Q9NP79)

PDB	External Database	Details
Ser 0	-	expression tag

C: 139 - 195 (UniProt: Q9NZZ3)

PDB	External Database	Details
Ser 138	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	27700.1
Non-Polymers*	Number of molecules	10
	Total formula weight	617.7
All*	Total formula weight	28317.7

*Water molecules are not included.