4TVA

Universal Pathway for Post-Transfer Editing Reactions: Insight from Crystal structure of TthPheRS with Puromycine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Phenylalanine--tRNA ligase alpha subunit	polymer	350	39309.2	1	UniProt (P27001)	Thermus thermophilus	Phenylalanyl-tRNA synthetase alpha subunit,PheRS
2	B (B)	Phenylalanine--tRNA ligase beta subunit	polymer	785	86720.7	1	UniProt (P27002) Pfam (PF03483) Pfam (PF03484) Pfam (PF17759) Pfam (PF03147) UniProt (by SIFTS) (Q5SGX1)	Thermus thermophilus	Phenylalanyl-tRNA synthetase beta subunit,PheRS
3	C (A)	PHENYLALANINE	non-polymer		165.2	1	Chemie (PHE) PubChem (994) PubChem (6140) PubChem (71567)
4	D (B)	PUROMYCIN	non-polymer		471.5	1	Chemie (PUY) PubChem (16760051) PubChem (4984) PubChem (5891) PubChem (23615943) PubChem (177678906) PubChem (439530) PubChem (25202279) PubChem (1712112) PubChem (40469853) PubChem (44120104) PubChem (51340256) PubChem (51340724) PubChem (57614967) PubChem (2724365) PubChem (58811233) PubChem (58811244) PubChem (5351455) PubChem (5702164) PubChem (73952279) PubChem (6602487) PubChem (6604191) PubChem (91711144) PubChem (1548891) PubChem (11953804) PubChem (94860682) PubChem (94860683) PubChem (94860684) PubChem (95566333) PubChem (95907090) PubChem (97289755) PubChem (98617641) PubChem (92403519) PubChem (6102313) PubChem (6560136) PubChem (6610289) PubChem (124504893) PubChem (12193264) PubChem (124504894) PubChem (12314760) PubChem (131676367) PubChem (134692731) PubChem (135391169) PubChem (137658626) PubChem (168313088) PubChem (170842883) PubChem (155061105) PubChem (162911390) PubChem (166947121)
5	E, F (A, B)	water	water		18.0	175	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	126029.9
Non-Polymers*	Number of molecules	2
	Total formula weight	636.7
All*	Total formula weight	126666.6

*Water molecules are not included.