4TT7
Crystal structure of human ALK with a covalent modification
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALK tyrosine kinase receptor | polymer | 325 | 36770.2 | 1 | UniProt (Q9UM73) Pfam (PF07714) | Homo sapiens (Human) | Anaplastic lymphoma kinase |
| 2 | B, C (A) | 1-THIOETHANESULFONIC ACID | non-polymer | 142.2 | 2 | Chemie (COM) | |||
| 3 | D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | G (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 1095 - 1410 (UniProt: Q9UM73)
| PDB | External Database | Details |
|---|---|---|
| Met 1094 | - | initiating methionine |
| Leu 1411 | - | expression tag |
| Glu 1412 | - | expression tag |
| His 1413 | - | expression tag |
| His 1414 | - | expression tag |
| His 1415 | - | expression tag |
| His 1416 | - | expression tag |
| His 1417 | - | expression tag |
| His 1418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36770.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 470.6 | |
| All* | Total formula weight | 37240.8 |
