4TT7

Crystal structure of human ALK with a covalent modification

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ALK tyrosine kinase receptor	polymer	325	36770.2	1	UniProt (Q9UM73) Pfam (PF07714) In PDB	Homo sapiens (Human)	Anaplastic lymphoma kinase
2	A	1-THIOETHANESULFONIC ACID	non-polymer		142.2	2	Chemie (COM)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
4		water	water		18.0	159	Chemie (HOH)

Sequence modifications

A: 1095 - 1410 (UniProt: Q9UM73)

PDB	External Database	Details
Met 1094	-	initiating methionine
Leu 1411	-	expression tag
Glu 1412	-	expression tag
His 1413	-	expression tag
His 1414	-	expression tag
His 1415	-	expression tag
His 1416	-	expression tag
His 1417	-	expression tag
His 1418	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36770.2
Non-Polymers*	Number of molecules	5
	Total formula weight	470.6
All*	Total formula weight	37240.8

*Water molecules are not included.