4TRO
Structure of the enoyl-ACP reductase of Mycobacterium tuberculosis InhA, inhibited with the active metabolite of isoniazid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28554.8 | 1 | UniProt (M9TGV3) Pfam (PF13561) UniProt (by SIFTS) (P9WGR1) | Mycobacterium tuberculosis | |
| 2 | B (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 3 | C (A) | ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE | non-polymer | 768.5 | 1 | Chemie (ZID) | |||
| 4 | D, E (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | F, G, H, I (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 6 | J, K (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | L (A) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28554.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2267.1 | |
| All* | Total formula weight | 30821.8 |
