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4TQP

Human transthyretin (TTR) complexed with (R)-3-(9H-fluoren-9-ylideneaminooxy)-2-methyl-N-(methylsulfonyl) propionamide in a dual binding mode

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transthyretinpolymer12713777.42UniProt (P02766)
Pfam (PF00576)
Homo sapiens (Human)ATTR,Prealbumin,TBPA
2C, E
(A, B)
(2R)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methyl-N-(methylsulfonyl)propanamidenon-polymer358.42Chemie (48R)
3D, F
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
4G, H
(A, B)
waterwater18.0260Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27554.7
Non-Polymers*Number of molecules4
Total formula weight901.0
All*Total formula weight28455.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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