4TQD
Crystal Structure of the C-terminal domain of IFRS bound with 3-iodo-L-Phe and ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pyrrolysine--tRNA ligase | polymer | 291 | 33399.2 | 1 | UniProt (Q8PWY1) Pfam (PF01409) | Methanosarcina mazei | Pyrrolysine--tRNA(Pyl) ligase,Pyrrolysyl-tRNA synthetase,PylRS |
| 2 | B, C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | E (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | F (A) | 3-iodo-L-phenylalanine | non-polymer | 291.1 | 1 | Chemie (33S) | |||
| 5 | G, H, I, J, K... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 6 | N (A) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A: 185 - 454 (UniProt: Q8PWY1)
| PDB | External Database | Details |
|---|---|---|
| Met 164 | - | expression tag |
| Gly 165 | - | expression tag |
| Ser 166 | - | expression tag |
| Ser 167 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| Ser 174 | - | expression tag |
| Ser 175 | - | expression tag |
| Gly 176 | - | expression tag |
| Leu 177 | - | expression tag |
| Val 178 | - | expression tag |
| Pro 179 | - | expression tag |
| Arg 180 | - | expression tag |
| Gly 181 | - | expression tag |
| Ser 182 | - | expression tag |
| His 183 | - | expression tag |
| Met 184 | - | expression tag |
| Ser 346 | Asn 346 | engineered mutation |
| Ile 348 | Cys 348 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33399.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1305.7 | |
| All* | Total formula weight | 34704.9 |
