4TNT
Structure of the human mineralocorticoid receptor in complex with DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Mineralocorticoid receptor | polymer | 103 | 11285.9 | 2 | UniProt (P08235) Pfam (PF00105) In PDB | Homo sapiens (Human) | MR,Nuclear receptor subfamily 3 group C member 2 |
2 | C | DNA (5'-D(*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3') | polymer | 17 | 5162.4 | 1 | synthetic construct | ||
3 | D | DNA (5'-D(*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3') | polymer | 17 | 5251.4 | 1 | synthetic construct | ||
4 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
5 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 593 - 671 (UniProt: P08235)
PDB | External Database | Details |
---|---|---|
Met 569 | - | initiating methionine |
His 570 | - | expression tag |
His 571 | - | expression tag |
His 572 | - | expression tag |
His 573 | - | expression tag |
His 574 | - | expression tag |
His 575 | - | expression tag |
Ser 576 | - | expression tag |
Ser 577 | - | expression tag |
Gly 578 | - | expression tag |
Val 579 | - | expression tag |
Asp 580 | - | expression tag |
Leu 581 | - | expression tag |
Gly 582 | - | expression tag |
Thr 583 | - | expression tag |
Glu 584 | - | expression tag |
Asn 585 | - | expression tag |
Leu 586 | - | expression tag |
Tyr 587 | - | expression tag |
Phe 588 | - | expression tag |
Gln 589 | - | expression tag |
Ser 590 | - | expression tag |
Asn 591 | - | expression tag |
Ala 592 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 32985.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 261.6 | |
All* | Total formula weight | 33247.2 |