4TNT
Structure of the human mineralocorticoid receptor in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mineralocorticoid receptor | polymer | 103 | 11285.9 | 2 | UniProt (P08235) Pfam (PF00105) | Homo sapiens (Human) | MR,Nuclear receptor subfamily 3 group C member 2 |
| 2 | C (C) | DNA (5'-D(*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3') | polymer | 17 | 5162.4 | 1 | synthetic construct | ||
| 3 | D (D) | DNA (5'-D(*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3') | polymer | 17 | 5251.4 | 1 | synthetic construct | ||
| 4 | E, F, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 593 - 671 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Met 569 | - | initiating methionine |
| His 570 | - | expression tag |
| His 571 | - | expression tag |
| His 572 | - | expression tag |
| His 573 | - | expression tag |
| His 574 | - | expression tag |
| His 575 | - | expression tag |
| Ser 576 | - | expression tag |
| Ser 577 | - | expression tag |
| Gly 578 | - | expression tag |
| Val 579 | - | expression tag |
| Asp 580 | - | expression tag |
| Leu 581 | - | expression tag |
| Gly 582 | - | expression tag |
| Thr 583 | - | expression tag |
| Glu 584 | - | expression tag |
| Asn 585 | - | expression tag |
| Leu 586 | - | expression tag |
| Tyr 587 | - | expression tag |
| Phe 588 | - | expression tag |
| Gln 589 | - | expression tag |
| Ser 590 | - | expression tag |
| Asn 591 | - | expression tag |
| Ala 592 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 32985.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 33247.2 |
