4TN7
Crystal structure of mouse KDM2A-H3K36ME-NO complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Lysine-specific demethylase 2A | polymer | 329 | 39031.3 | 2 | UniProt (P59997) Pfam (PF17811) | Mus musculus (Mouse) | F-box and leucine-rich repeat protein 11,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,[Histone-H3]-lysine-36 demethylase 1A |
| 2 | B, D (B, D) | Lysine-specific demethylase 2A | polymer | 68 | 7534.8 | 2 | UniProt (P59997) | Mus musculus (Mouse) | F-box and leucine-rich repeat protein 11,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,[Histone-H3]-lysine-36 demethylase 1A |
| 3 | E, F (E, F) | Peptide | polymer | 15 | 1652.9 | 2 | UniProt (by SIFTS) (P68431) | Homo sapiens | |
| 4 | G, J (A, C) | FE (III) ION | non-polymer | 55.8 | 2 | Chemie (FE) | |||
| 5 | H (A) | NITRIC OXIDE | non-polymer | 30.0 | 1 | Chemie (NO) | |||
| 6 | I, K (A, C) | SUCCINIC ACID | non-polymer | 118.1 | 2 | Chemie (SIN) | |||
| 7 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence modifications
A, C: 36 - 364 (UniProt: P59997)
| PDB | External Database | Details |
|---|---|---|
| Arg 159 | Trp 159 | conflict |
| Met 202 | Ile 202 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 96438.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 377.9 | |
| All* | Total formula weight | 96815.9 |
