4TN7
Crystal structure of mouse KDM2A-H3K36ME-NO complex
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue FE A 601 |
| Chain | Residue |
| A | HIS212 |
| A | ASP214 |
| A | HIS284 |
| A | NO602 |
| A | SIN603 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue NO A 602 |
| Chain | Residue |
| E | MLZ36 |
| A | HIS212 |
| A | ASP214 |
| A | FE601 |
| A | SIN603 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SIN A 603 |
| Chain | Residue |
| A | ASN142 |
| A | THR209 |
| A | HIS212 |
| A | TYR222 |
| A | LYS229 |
| A | HIS284 |
| A | VAL286 |
| A | FE601 |
| A | NO602 |
| E | MLZ36 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue FE C 601 |
| Chain | Residue |
| C | HIS212 |
| C | ASP214 |
| C | HIS284 |
| C | SIN602 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue SIN C 602 |
| Chain | Residue |
| C | ASN142 |
| C | ILE144 |
| C | THR209 |
| C | HIS212 |
| C | TYR222 |
| C | LYS229 |
| C | HIS284 |
| C | VAL286 |
| C | FE601 |
| F | MLZ36 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:15983376, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | MLZ36 | |
| F | MLZ36 | |
| D | LYS505 | |
| C | LYS229 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine => ECO:0000269|PubMed:15983376 |
| Chain | Residue | Details |
| E | LYS37 | |
| F | LYS37 | |
| A | HIS284 | |
| C | HIS212 | |
| C | ASP214 | |
| C | HIS284 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:19783980 |
| Chain | Residue | Details |
| E | TYR41 | |
| F | TYR41 |
