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4TKN

Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Sorting nexin-17polymer28632469.13UniProt (Q15036)
Pfam (PF21273)
Pfam (PF21271)
Pfam (PF18116)
Homo sapiens (Human)
2D, E, F
(D, E, F)
Krev interaction trapped protein 1polymer191924.13UniProt (O00522)Homo sapiens (Human)Krev interaction trapped 1,Cerebral cavernous malformations 1 protein
3G, H, I
(A, B, C)
waterwater18.048Chemie (HOH)
Sequence modifications
A, B, C: 108 - 391 (UniProt: Q15036)
PDBExternal DatabaseDetails
Gly 106-expression tag
Ser 107-expression tag
D, E, F: 225 - 237 (UniProt: O00522)
PDBExternal DatabaseDetails
Gly 219-expression tag
Pro 220-expression tag
Leu 221-expression tag
Gly 222-expression tag
Ser 223-expression tag
Pro 224-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight103179.4
All*Total formula weight103179.4
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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