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4S1S

Crystal structure of a VRC01-lineage antibody, 45-VRC01.H5.F-185917, in complex with clade A/E HIV-1 gp120 core

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1Gclade A/E 93TH057 HIV-1 gp120 corepolymer35339211.41Pfam (PF00516)
UniProt (by SIFTS) (A0A0M3KKW9)
In PDB
Human immunodeficiency virus 1 (HIV-1)
2HFab of VRC01-lineage antibody,45-VRC01.H5.F-185917 heavy chainpolymer22824790.01Homo sapiens
3LFab of VRC01 light chainpolymer21023089.61Homo sapiens
4G2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
5G4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87091.1
Non-Polymers*Number of molecules11
Total formula weight2450.4
All*Total formula weight89541.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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