4S0H

TBX5 DB, NKX2.5 HD, ANF DNA Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, E)	T-box transcription factor TBX5	polymer	186	21396.8	2	UniProt (Q99593) Pfam (PF00907)	Homo sapiens (human)	T-box protein 5
2	B, D (B, F)	Homeobox protein Nkx-2.5	polymer	53	6531.5	2	UniProt (P52952) Pfam (PF00046)	Homo sapiens (human)	Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E
3	E, G (C, G)	5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP*TP*GP*AP*AP*GP*TP*GP*G)-3'	polymer	19	5795.8	2		synthetic construct
4	F, H (D, H)	5'-D(*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP*A)-3'	polymer	19	5853.8	2		synthetic construct
5	I, J (F, C)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

B, F: 142 - 194 (UniProt: P52952)

PDB	External Database	Details
Ser 193	Cys 193	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	79155.8
All*	Total formula weight	79155.8

*Water molecules are not included.