4S0H

TBX5 DB, NKX2.5 HD, ANF DNA Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription
E	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0005634	cellular_component	nucleus
E	0006355	biological_process	regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
F	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
F	0003677	molecular_function	DNA binding
F	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LAsvLkLTstQVKIWFqNrryksK

Chain	Residue	Details
B	LEU171-LYS194

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site_id	PS01264
Number of Residues	19
Details	TBOX_2 T-box domain signature 2. VHPDSpatGahWMrqlVsF

Chain	Residue	Details
A	VAL137-PHE155

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site_id	PS01283
Number of Residues	20
Details	TBOX_1 T-box domain signature 1. LWlkFhevgTEMIITkaGRR

Chain	Residue	Details
A	LEU63-ARG82

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	360
Details	DNA_BIND: T-box => ECO:0000255|PROSITE-ProRule:PRU00201, ECO:0000269|PubMed:26926761

Chain	Residue	Details
A	LEU58-GLY238
E	LEU58-GLY238

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