4RZ1

RENIN IN COMPLEXED WITH (3S,4S)-4-({[4-methoxy-3-(3-methoxypropoxy)benzoyl](propan-2-yl)amino}methyl)pyrrolidin-3-yl benzylcarbamate INHIBITOR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Renin	polymer	340	37267.0	2	UniProt (P00797) Pfam (PF00026)	Homo sapiens	Angiotensinogenase
2	C, F (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D, G (A, B)	(3S,4S)-4-({[4-methoxy-3-(3-methoxypropoxy)benzoyl](propan-2-yl)amino}methyl)pyrrolidin-3-yl benzylcarbamate	non-polymer		513.6	2	Chemie (3ZN)
4	E (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	H, I (B)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
6	J, K (A, B)	water	water		18.0	178	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74534.0
Non-Polymers*	Number of molecules	7
	Total formula weight	1722.0
All*	Total formula weight	76256.0

*Water molecules are not included.