4RYX
Crystal structure of RPE65 in complex with emixustat and palmitate, P6522 crystal form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Retinoid isomerohydrolase | polymer | 533 | 61040.2 | 1 | UniProt (Q28175) Pfam (PF03055) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | All-trans-retinyl-palmitate hydrolase, Retinal pigment epithelium-specific 65 kDa protein, Retinol isomerase |
2 | A | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
3 | A | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
4 | A | (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol | non-polymer | 263.4 | 1 | Chemie (A3V) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
6 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
7 | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
A: 1 - 533 (UniProt: Q28175)
PDB | External Database | Details |
---|---|---|
Leu 341 | Ser 341 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 61040.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1026.2 | |
All* | Total formula weight | 62066.4 |