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4RXA

Crystal structure of human farnesyl diphosphate synthase in complex with BPH-1358

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AFarnesyl pyrophosphate synthasepolymer34840029.71UniProt (P14324)
Pfam (PF00348)
In PDB
Homo sapiens (human)FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase
2AN,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]biphenyl-4,4'-dicarboxamidenon-polymer528.61Chemie (3F2)
3APHOSPHATE IONnon-polymer95.01Chemie (PO4)
4waterwater18.0104Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40029.7
Non-Polymers*Number of molecules2
Total formula weight623.6
All*Total formula weight40653.3
*Water molecules are not included.

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PDB entries from 2024-08-21

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