4RXA
Crystal structure of human farnesyl diphosphate synthase in complex with BPH-1358
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyl pyrophosphate synthase | polymer | 348 | 40029.7 | 1 | UniProt (P14324) Pfam (PF00348) | Homo sapiens (human) | FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase |
| 2 | B (A) | N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]biphenyl-4,4'-dicarboxamide | non-polymer | 528.6 | 1 | Chemie (3F2) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40029.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 623.6 | |
| All* | Total formula weight | 40653.3 |
