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4RWY

Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHIV-1 YU2 gp120polymer37641695.41Pfam (PF00516)
UniProt (by SIFTS) (P35961)
In PDB
Human immunodeficiency virus 1 (HIV-1)
2HAntibody 8ANC131 Heavy chainpolymer22724302.51Homo sapiens (human)
3LAntibody 8ANC131 Light chainpolymer21323453.11Homo sapiens (human)
4A2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.26Chemie (NAG)
5A4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
6A, H1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
7HSODIUM IONnon-polymer23.01Chemie (NA)
8waterwater18.0231Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight89451.0
Non-Polymers*Number of molecules13
Total formula weight1898.9
All*Total formula weight91349.9
*Water molecules are not included.

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PDB entries from 2024-04-24

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