4RWY
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 YU2 gp120 | polymer | 376 | 41695.4 | 1 | Pfam (PF00516) UniProt (by SIFTS) (P35961) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | B (H) | Antibody 8ANC131 Heavy chain | polymer | 227 | 24302.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | Antibody 8ANC131 Light chain | polymer | 213 | 23453.1 | 1 | Homo sapiens (human) | ||
| 4 | D, E, F, G, H... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 5 | J (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 6 | K, L, M, N, O (A, H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 7 | P (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | Q, R, S (A, H, L) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89451.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1898.9 | |
| All* | Total formula weight | 91349.9 |
